Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.52 |
| ▸ | SCN1A | P35498 | 17/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634143 | 0.87 | SCN8A (0.51) | SCN8ASCN1A | |
| SCHEMBL19613397 | 0.85 | SCN8A (0.60) | SCN8ASCN1A | |
| SCHEMBL19634139 | 0.85 | MAPT (0.39) | SCN8ASCN1AMEN1KMT2A | |
| SCHEMBL19627628 | 0.81 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL19634090 | 0.79 | HTR2A (0.38) | SCN1AMEN1KMT2A | |
| SCHEMBL20095534 | 0.77 | HTR2A (0.36) | SCN1AMEN1KMT2A | |
| SCHEMBL20256208 | 0.77 | MEN1 (0.37) | SCN1AMEN1KMT2A | |
| SCHEMBL20256130 | 0.75 | CYP1A2 (0.37) | SCN8ASCN1AMEN1KMT2A | |
| SCHEMBL19633931 | 0.75 | SCN8A (0.71) | SCN8ASCN1A | |
| SCHEMBL20256513 | 0.75 | SCN1A (0.44) | SCN8ASCN1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |