Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783447 | 0.83 | SCN8A (0.33) | SCN8A | |
| SCHEMBL21783499 | 0.82 | SCN8A (0.32) | SCN8AKMT2A | |
| SCHEMBL21783364 | 0.81 | SCN8A (0.33) | SCN8A | |
| SCHEMBL21783346 | 0.78 | SCN8A (0.32) | SCN8ASSTR4 | |
| SCHEMBL19627632 | 0.77 | SCN8A (0.45) | SCN8ASLC16A3SLC16A1MCTS1MEN1 | |
| SCHEMBL21783459 | 0.76 | SCN8A (0.32) | SCN8A | |
| SCHEMBL19634117 | 0.76 | SCN8A (0.37) | SCN8ASSTR4 | |
| SCHEMBL19633980 | 0.76 | SCN8A (0.35) | SCN8A | |
| SCHEMBL20256852 | 0.73 | SCN8A (0.34) | SCN8A | |
| SCHEMBL19633949 | 0.73 | SCN8A (0.38) | SCN8ASSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |