Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783447 | 0.83 | SCN8A (0.33) | SCN8A | |
| SCHEMBL21783364 | 0.82 | SCN8A (0.33) | SCN8A | |
| SCHEMBL19634149 | 0.82 | SCN8A (0.35) | SCN8AKMT2A | |
| SCHEMBL19633949 | 0.75 | SCN8A (0.38) | SCN8A | |
| SCHEMBL21783501 | 0.75 | SMN1; SMN2 (0.42) | SCN8ALMNAKMT2AGAA | |
| SCHEMBL30045772 | 0.75 | SMN1; SMN2 (0.42) | SCN8ALMNAKMT2AGAA | |
| SCHEMBL19633980 | 0.74 | SCN8A (0.35) | SCN8A | |
| SCHEMBL19634054 | 0.73 | SCN8A (0.38) | SCN8A | |
| SCHEMBL20256898 | 0.73 | SCN8A (0.35) | SCN8A | |
| SCHEMBL21783506 | 0.72 | SCN8A (0.34) | SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |