Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 15/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 15/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 14/20 | 0.33 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634115 | 0.79 | SCN8A (0.34) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL19634007 | 0.74 | SCN8A (0.69) | SCN1ASCN8ASCN5A | |
| SCHEMBL21117772 | 0.72 | SCN8A (0.58) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL20256953 | 0.72 | SCN1A (0.70) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL20256697 | 0.72 | SCN1A (0.70) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL20256890 | 0.71 | SCN8A (0.70) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL21794067 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL21793939 | 0.67 | SCN1A (0.34) | SCN1ASCN8ASCN5A | |
| SCHEMBL19634337 | 0.65 | SCN1A (0.33) | SCN1ASCN8ASCN5ASCN1B | |
| SCHEMBL21783431 | 0.65 | SCN1A (0.32) | SCN1ASCN8ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |