Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447385 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL19627672 | 0.95 | SCN8A (0.36) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL19627654 | 0.93 | SCN1A (0.44) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL29447393 | 0.92 | SCN8A (0.44) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL19627652 | 0.92 | SCN8A (0.44) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL19614139 | 0.92 | SCN8A (0.40) | MMP1MMP9MMP3SCN8AMMP13 | |
| SCHEMBL19614141 | 0.92 | SCN8A (0.40) | MMP1MMP9MMP3SCN8AMMP13 | |
| SCHEMBL30845610 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL21789465 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP9MMP3MMP7 | |
| SCHEMBL28556812 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |