Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448415 | 0.83 | MEN1 (0.31) | MEN1KMT2APSMB1PSMB5PSMB2 | |
| SCHEMBL4094205 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9275856 | 0.76 | CARM1 (0.35) | TSHRTDP1 | |
| SCHEMBL24891399 | 0.74 | HRH3 (0.39) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL12191564 | 0.74 | HRH3 (0.39) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL22342735 | 0.74 | HRH3 (0.39) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL3630893 | 0.74 | HRH3 (0.39) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL135698 | 0.74 | HRH3 (0.39) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL17886533 | 0.72 | HRH3 (0.38) | MEN1KMT2APSMB1PSMB5HRH3 | |
| SCHEMBL19766585 | 0.71 | ATM (0.41) | MEN1KMT2ANPSR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |