Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471324 | 0.98 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL21016223 | 0.98 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL19634651 | 0.94 | GNAI3 (0.41) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL793522 | 0.90 | GNAI3 (0.53) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL6553947 | 0.90 | GNAI3 (0.53) | GNAI3GNAO1GNAI1LTA4HMEN1 | |
| SCHEMBL21477156 | 0.89 | GNAI3 (0.46) | GNAI3GNAO1GNAI1LTA4HHRH3 | |
| SCHEMBL10960846 | 0.89 | HRH3 (0.39) | GNAI3GNAO1GNAI1ALDH1A1HRH3 | |
| SCHEMBL21106252 | 0.88 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HMEN1 | |
| SCHEMBL23471206 | 0.88 | GNAI3 (0.57) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| Bromide SCHEMBL28255534 | 0.88 | GNAI3 (0.52) | GNAI3GNAO1GNAI1LTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |