Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634706 | 0.88 | PARP1 (0.58) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL10720054 | 0.87 | LMNA (0.61) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634649 | 0.87 | MEN1 (0.50) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL2322582 | 0.86 | SMN1; SMN2 (0.57) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634743 | 0.86 | MEN1 (0.52) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634643 | 0.84 | DRD3 (0.52) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634465 | 0.84 | KMT2A (0.50) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634710 | 0.83 | MEN1 (0.54) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634707 | 0.83 | MEN1 (0.60) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL24732812 | 0.82 | HPGD (0.59) | MEN1KMT2ALMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |