Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 9/20 | 0.54 |
| ▸ | DRD2 | P14416 | 8/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21015352 | 0.87 | KMT2A (0.53) | NAMPTDRD3DRD2KCNA5KMT2A | |
| SCHEMBL23471208 | 0.86 | KMT2A (0.61) | NAMPTDRD2KMT2AMEN1ALDH1A1 | |
| SCHEMBL19634458 | 0.84 | KMT2A (0.48) | DRD3DRD2KMT2AMEN1ALDH1A1 | |
| SCHEMBL23471207 | 0.83 | KMT2A (0.50) | NAMPTDRD2KMT2AMEN1ALDH1A1 | |
| SCHEMBL23471231 | 0.81 | KMT2A (0.54) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL763421 | 0.80 | KCNA5 (0.70) | NAMPTDRD3DRD2KCNA5ALDH1A1 | |
| SCHEMBL16358258 | 0.79 | DRD3 (0.61) | NAMPTDRD3DRD2KCNA5KMT2A | |
| SCHEMBL19145557 | 0.79 | DRD3 (0.61) | NAMPTDRD3DRD2KCNA5ALDH1A1 | |
| SCHEMBL23730162 | 0.79 | DRD3 (0.58) | NAMPTDRD3DRD2KCNA5 | |
| SCHEMBL19634454 | 0.79 | KMT2A (0.67) | NAMPTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |