Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471231 | 0.87 | KMT2A (0.54) | KMT2AMAPK10MEN1HDAC1HDAC6 | |
| SCHEMBL21015765 | 0.87 | HDAC6 (0.49) | KMT2ADRD2MAPK8MAPK10MEN1 | |
| SCHEMBL19634722 | 0.84 | NAMPT (0.55) | KMT2ADRD2MEN1HDAC1HDAC6 | |
| SCHEMBL19634410 | 0.83 | DRD2 (0.50) | KMT2ADRD2MEN1ALDH1A1MAPT | |
| SCHEMBL23471208 | 0.82 | KMT2A (0.61) | KMT2ADRD2MAPK10MEN1HDAC1 | |
| SCHEMBL23471207 | 0.79 | KMT2A (0.50) | KMT2ADRD2MAPK10MEN1HDAC1 | |
| SCHEMBL19634457 | 0.78 | HPGD (0.59) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL19634454 | 0.77 | KMT2A (0.67) | KMT2AMAPK10MEN1HDAC1HDAC6 | |
| SCHEMBL8409443 | 0.74 | SLC6A7 (0.54) | KMT2ADRD2MEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8714344 | 0.74 | KDM1A (0.54) | KMT2ADRD2MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |