Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.42 |
| ▸ | GYS1 | P13807 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471242 | 0.84 | HDAC3 (0.43) | SLC7A5GYS1PPARGKMT2AL3MBTL1 | |
| SCHEMBL21015940 | 0.81 | NR1H4 (0.42) | GYS1PPARGKMT2AL3MBTL1NPC1 | |
| SCHEMBL23471101 | 0.78 | HDAC3 (0.46) | LOXL2SLC7A5KMT2ANPC1LMNA | |
| SCHEMBL15601880 | 0.78 | PPARG (0.52) | SLC7A5GYS1PPARGKMT2AL3MBTL1 | |
| SCHEMBL19634703 | 0.76 | HPGD (0.63) | LOXL2PPARGKMT2AL3MBTL1NPC1 | |
| SCHEMBL23471099 | 0.76 | HDAC3 (0.42) | LOXL2SLC7A5NPC1LMNARAB9A | |
| SCHEMBL21015942 | 0.75 | NR1H4 (0.43) | LOXL2NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL27926873 | 0.75 | LOXL2 (0.69) | LOXL2SLC7A5CFDKMT2ANPC1 | |
| SCHEMBL15592540 | 0.74 | FOLH1 (0.46) | SLC7A5GYS1PPARGKMT2AL3MBTL1 | |
| SCHEMBL19634694 | 0.74 | HDAC6 (0.47) | LOXL2PPARGKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |