Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | SHBG | P04278 | 5/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.69 |
| ▸ | PGR | P06401 | 4/20 | 0.69 |
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.69 |
| ▸ | SNCA | P37840 | 2/20 | 0.69 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.69 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.69 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475606 | 1.00 | CYP3A4 (0.69) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL10796253 | 1.00 | CYP3A4 (0.69) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL21367235 | 1.00 | CYP3A4 (0.69) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL20402646 | 1.00 | CYP3A4 (0.69) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL11572462 | 0.93 | CYP3A4 (0.70) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL6462109 | 0.91 | CYP3A4 (0.72) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL13310373 | 0.91 | CYP3A4 (0.72) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL6462115 | 0.91 | CYP3A4 (0.72) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL9351748 | 0.91 | CYP3A4 (0.72) | CYP3A4LMNAMAPTSHBGTSHR | |
| SCHEMBL22475748 | 0.89 | LMNA (0.66) | CYP3A4LMNAMAPTSHBGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199036-A1 | PROCESS AND INTERMEDIATES FOR THE 6,7-ALPHA-EPOXIDATION OF STEROID 4,6-DIENES | NZP UK Limited (GB) | 2017-11-23 | — | — | WO | disclosed |