Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635154 | 0.89 | ABCB1 (0.33) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19846795 | 0.86 | ABCB1 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20281372 | 0.82 | ABCB1 (0.40) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19635146 | 0.81 | ABCB1 (0.33) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20362560 | 0.81 | ABCB1 (0.40) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12324196 | 0.77 | ABCB1 (0.44) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13043465 | 0.77 | ABCB1 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL23481213 | 0.76 | ABCB1 (0.33) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL21648602 | 0.75 | AR (0.35) | ABCB1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL21165046 | 0.75 | USP2 (0.35) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201531-A1 | PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2017-11-23 | — | — | WO | disclosed |