SCHEMBL21165046

SCHEMBL21165046

O=S(=O)(O)c1ccccc1-c1c2ccc(=[N+]3CCCCC3)cc-2oc2cc(N3CCCCC3)ccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.35
▸ NFKB1 P19838 2/20 0.35
▸ KDM4A O75164 1/20 0.35
▸ NSD2 O96028 1/20 0.35
▸ ALPL P05186 1/20 0.35
▸ PLCG1 P19174 1/20 0.35
▸ TNNI3 P19429 1/20 0.35
▸ TNNT2 P45379 1/20 0.35
▸ MMP14 P50281 1/20 0.35
▸ CASP6 P55212 1/20 0.35
▸ TNNC1 P63316 1/20 0.35
▸ KDM4C Q9H3R0 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ PGAM1 P18669 2/20 0.33
▸ ABCB1 P08183 1/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ GFER P55789 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15432772 0.85 PDK2 (0.32) USP2NFKB1KDM4ANSD2ALPL
SCHEMBL21648602 0.84 AR (0.35) ABCB1KMT2AALDH1A1GAAMAPT
SCHEMBL26505115 0.83 ABCB1 (0.40) USP2L3MBTL1ABCB1KMT2ATDP1
SCHEMBL21648600 0.81 MEN1 (0.43) USP2KMT2ATDP1ASAH1ATM
SCHEMBL12317621 0.81 PGAM1 (0.33) USP2PGAM1KMT2AASAH1ATM
SCHEMBL12324196 0.80 ABCB1 (0.44) USP2L3MBTL1ABCB1KMT2AMAPT
SCHEMBL13966980 0.80 PDK2 (0.31) PDK2
SCHEMBL20281372 0.80 ABCB1 (0.40) USP2ALPLL3MBTL1ABCB1KMT2A
SCHEMBL19635146 0.79 ABCB1 (0.33) USP2ABCB1KMT2AALDH1A1GAA
SCHEMBL20362560 0.79 ABCB1 (0.40) USP2L3MBTL1ABCB1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 USP2 616/4885NFKB1 3261/4885KDM4A 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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