Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231646 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL2236272 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL13352076 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL2235295 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL2235444 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL12348817 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL12345663 | 1.00 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL2234690 | 0.98 | PLA2G2C (0.64) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL2231204 | 0.97 | PLA2G2C (0.58) | PLA2G2CLPAR1LPAR3LPAR2TLR2 | |
| SCHEMBL10141359 | 0.90 | PLA2G2C (0.63) | PLA2G2CLPAR1LPAR3LPAR2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |