SCHEMBL10141359

SCHEMBL10141359

CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCCN)OCCCCCCC(=O)OCC

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.63
LPAR1 Q92633 5/20 0.56
LPAR3 Q9UBY5 5/20 0.56
P2RY10 O00398 4/20 0.52
GPR34 Q9UPC5 2/20 0.52
FABP3 P05413 1/20 0.52
LPAR2 Q9HBW0 1/20 0.50
TLR2 O60603 1/20 0.47
ENPP2 Q13822 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10141356 1.00 PLA2G2C (0.63) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL2236440 1.00 PLA2G2C (0.63) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL13105326 0.98 PLA2G2C (0.60) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL13105323 0.98 PLA2G2C (0.63) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL2235444 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL12348817 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL2231646 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL13352076 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL1963535 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34
SCHEMBL2236272 0.90 PLA2G2C (0.64) PLA2G2CLPAR1LPAR3P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 US disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 US disclosed
US-9006217-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-04-14 US disclosed
US-8802875-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-08-12 US disclosed
US-8759557-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-06-24 US disclosed
US-8569529-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-10-29 US disclosed
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-06-20 US disclosed
US-20130079540-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-03-28 US disclosed
US-8124800-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2012-02-28 US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 PLA2G2C 19/4885LPAR1 199/4885LPAR3 323/4885
US-20130079540-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2C 14/4885LPAR1 77/4885LPAR3 114/4885
US-20150216882-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2C 13/4885LPAR1 71/4885LPAR3 126/4885
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2C 19/4885LPAR1 199/4885LPAR3 323/4885
US-20170246197-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2C 13/4885LPAR1 71/4885LPAR3 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.