Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20623216 | 0.93 | GNAI3 (0.41) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL30299418 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL22534819 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL30284659 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL20618496 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL19040726 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL20618494 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL21423426 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL19032602 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 | |
| SCHEMBL29329334 | 0.92 | GNAI3 (0.40) | GNAI3GNAI1L3MBTL1CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201332-A1 | POLYNUCLEOTIDES ENCODING ACYL-COA DEHYDROGENASE, VERY LONG-CHAIN FOR THE TREATMENT OF VERY LONG-CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |