Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 16/20 | 0.48 |
| ▸ | BAD | Q92934 | 4/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.44 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24594219 | 0.87 | MCL1 (0.59) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19615342 | 0.87 | MCL1 (0.63) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19635951 | 0.85 | MCL1 (0.47) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19635574 | 0.85 | MCL1 (0.55) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL24378130 | 0.85 | MCL1 (0.47) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19636011 | 0.84 | MCL1 (0.66) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19635078 | 0.79 | MCL1 (0.56) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL24594089 | 0.79 | MCL1 (0.57) | MCL1BADBCL2L1 | |
| SCHEMBL24594152 | 0.79 | MCL1 (0.60) | MCL1BADBCL2L1BCL2 | |
| SCHEMBL19635422 | 0.79 | MCL1 (0.56) | MCL1BADBCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |