Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.58 |
| ▸ | BLK | P51451 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635642 | 1.00 | BTK (0.58) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635646 | 1.00 | BTK (0.58) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635206 | 0.90 | BTK (0.68) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635205 | 0.90 | BTK (0.68) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635661 | 0.86 | BTK (0.54) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635662 | 0.86 | BTK (0.54) | BTKBLKEGFRLCKITK | |
| SCHEMBL19636022 | 0.86 | BTK (0.75) | BTKBLKEGFRLCKITK | |
| SCHEMBL19635809 | 0.86 | BTK (0.75) | BTKBLKEGFRLCKITK | |
| SCHEMBL20985194 | 0.86 | BTK (0.75) | BTKEGFR | |
| SCHEMBL19636124 | 0.86 | BTK (0.75) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198049-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |