Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.75 |
| ▸ | EGFR | P00533 | 7/20 | 0.67 |
| ▸ | BLK | P51451 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.64 |
| ▸ | ITK | Q08881 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636022 | 1.00 | BTK (0.75) | BTKEGFRBLKLCKJAK3 | |
| SCHEMBL19635649 | 0.93 | BTK (0.74) | BTKEGFRBLKLCKJAK3 | |
| SCHEMBL19635651 | 0.93 | BTK (0.74) | BTKEGFRBLKLCKJAK3 | |
| SCHEMBL28370674 | 0.88 | BTK (0.76) | BTKEGFRBLKLCKJAK3 | |
| SCHEMBL28370673 | 0.88 | BTK (0.76) | BTKEGFRBLKLCKJAK3 | |
| SCHEMBL19635790 | 0.87 | BTK (0.58) | BTKEGFRBLKLCKITK | |
| SCHEMBL19635643 | 0.87 | BTK (0.58) | BTKEGFRBLKLCKITK | |
| SCHEMBL19635810 | 0.87 | BTK (0.58) | BTKEGFRBLKLCKITK | |
| SCHEMBL19635642 | 0.86 | BTK (0.58) | BTKEGFRBLKLCKITK | |
| SCHEMBL19635646 | 0.86 | BTK (0.58) | BTKEGFRBLKLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198049-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |