Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 6/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184248 | 1.00 | LMNA (0.54) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL19636576 | 0.85 | CNR1 (0.50) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL28183374 | 0.84 | CNR2 (0.55) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL19636592 | 0.84 | CNR2 (0.55) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL29966020 | 0.79 | LMNA (0.63) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL31455664 | 0.74 | MAPT (0.59) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL28361450 | 0.73 | LMNA (0.53) | LMNAALDH1A1NPSR1CNR2CNR1 | |
| SCHEMBL19636457 | 0.71 | MCHR1 (0.44) | ALDH1A1CNR2CNR1MAPTPSEN1 | |
| SCHEMBL19636456 | 0.71 | MCHR1 (0.44) | ALDH1A1CNR2CNR1MAPTPSEN1 | |
| SCHEMBL19636714 | 0.71 | CNR2 (0.59) | ALDH1A1CNR2CNR1TAS2R14PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197670-A1 | METHOD FOR SYNTHESIZING 1,2-DIMETHYLENE CYCLOBUTANE CHIRAL COMPOUND | 中国科学院福建物质结构研究所 | 2017-11-23 | — | — | WO | disclosed |