Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022849 | 0.74 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL19610365 | 0.74 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1788259 | 0.74 | PIM1 (0.52) | PIM1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19610364 | 0.73 | PIM1 (0.42) | PIM1MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22406161 | 0.72 | PIM1 (0.51) | PIM1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15870942 | 0.69 | PIM1 (0.48) | PIM1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL213253 | 0.68 | PLA2G7 (0.65) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL213254 | 0.68 | PLA2G7 (0.65) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL18952163 | 0.68 | KDM1A (0.60) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL212294 | 0.67 | HTT (0.49) | MAPTSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198780-A1 | IMIDAZOLES AS HISTONE DEMETHYLASE INHIBITORS | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |