Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18970781 | 0.84 | — | — | |
| SCHEMBL22649517 | 0.84 | CYP4F2 (0.34) | — | |
| SCHEMBL27646333 | 0.80 | PRKCA (0.48) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL27625696 | 0.79 | PRKCA (0.42) | PRKCAALDH1A1 | |
| SCHEMBL27625810 | 0.78 | PRKCA (0.47) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL17693803 | 0.77 | POLB (0.42) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL1640996 | 0.75 | PRKCA (0.53) | PRKCA | |
| SCHEMBL538492 | 0.75 | PRKCA (0.53) | PRKCA | |
| SCHEMBL1426847 | 0.75 | PRKCA (0.44) | PRKCA | |
| SCHEMBL685935 | 0.75 | PRKCA (0.55) | PRKCAPOLBGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201347-A1 | POLYNUCLEOTIDES ENCODING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |