SCHEMBL19636705

SCHEMBL19636705

COc1ccc(CCC2CCC(C3CCC(C)CC3)CC2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
SLC6A4 P31645 7/20 0.36
SLC6A2 P23975 6/20 0.36
SLC6A3 Q01959 6/20 0.36
KCNH2 Q12809 1/20 0.34
QRFPR Q96P65 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17109959 0.96 ALDH1A1 (0.39) ALDH1A1SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL14205120 0.96 ALDH1A1 (0.39) ALDH1A1SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL20346143 0.89 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3KCNH2QRFPR
SCHEMBL17614878 0.89 SLC6A4 (0.36) ALDH1A1SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL19195164 0.89 HTR2A (0.36)
SCHEMBL16638478 0.88 ALDH1A1 (0.35) ALDH1A1
SCHEMBL19727264 0.88 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3KCNH2QRFPR
SCHEMBL14232332 0.87 SLC6A2 (0.35) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL12997680 0.86 ALDH1A1 (0.35) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL9060856 0.86 PDE4A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9835890-B2 Liquid crystal display MERCK PATENG GMBH (DE) 2017-12-05 US disclosed
US-20170335194-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-11-23 US disclosed