Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22756355 | 0.96 | GPR119 (0.46) | GPR119SLC2A1ALOX5APFEN1CSF1R | |
| SCHEMBL19610219 | 0.91 | GPR119 (0.45) | GPR119SLC2A1CSF1RKDM4EPKM | |
| SCHEMBL19610328 | 0.90 | GPR119 (0.45) | GPR119SLC2A1ALOX5APFEN1CSF1R | |
| SCHEMBL20744396 | 0.86 | CSF1R (0.43) | GPR119SLC2A1ALOX5APFEN1CSF1R | |
| SCHEMBL19610325 | 0.84 | PDE4D (0.50) | GPR119SLC2A1 | |
| SCHEMBL19409514 | 0.82 | GPR119 (0.48) | GPR119ALOX5APFEN1CSF1RKDM4E | |
| SCHEMBL1052671 | 0.81 | PDE4B (0.48) | GPR119SLC2A1CSF1RKDM4EPKM | |
| SCHEMBL1055480 | 0.78 | GPR119 (0.51) | GPR119SLC2A1CSF1R | |
| SCHEMBL1052689 | 0.78 | GPR119 (0.51) | GPR119SLC2A1CSF1R | |
| SCHEMBL19409668 | 0.78 | GPR119 (0.48) | GPR119CSF1RKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198780-A1 | IMIDAZOLES AS HISTONE DEMETHYLASE INHIBITORS | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |