SCHEMBL19636965

SCHEMBL19636965

C1=Cc2c(c3cc(-n4c5ccccc5c5ccccc54)ccc3n2-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3ccccc3)c2)CC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FAAH O00519 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
MGLL Q99685 1/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
WNK1 Q9H4A3 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21923269 0.98 ATM (0.36) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL21923270 0.97 ATM (0.38) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL21551570 0.97 ATM (0.37) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL24990024 0.96 ATM (0.38) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL17012686 0.96 ATM (0.39) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL26196489 0.95 ATM (0.38) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL26744566 0.95 ATM (0.35) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL21583501 0.92 ATM (0.35) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL26156841 0.92 L3MBTL1 (0.40) ATMKDM4EL3MBTL1ALDH1A1HTT
SCHEMBL26252230 0.92 KDM4E (0.42) ATMKDM4EL3MBTL1EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4273126-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4274404-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
WO-2017200210-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-11-23 WO disclosed