Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22320611 | 0.80 | ALDH1A1 (0.33) | EPHX1ALDH1A1 | |
| SCHEMBL28139936 | 0.78 | TSHR (0.38) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL1874859 | 0.76 | CYP2C19 (0.36) | ALDH1A1SMN1; SMN2DPP4FAPPITRM1 | |
| SCHEMBL21119350 | 0.74 | EPHX1 (0.33) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22766076 | 0.74 | EPHX1 (0.33) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5949673 | 0.74 | EPHX1 (0.33) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18052040 | 0.74 | EPHX1 (0.33) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5505300 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24012335 | 0.71 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL8411779 | 0.71 | ALDH1A1 (0.35) | EPHX1ALDH1A1SMN1; SMN2DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509957-A1 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070541-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |