Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917954 | 0.98 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 | |
| SCHEMBL17808170 | 0.97 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 | |
| SCHEMBL23095158 | 0.95 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 | |
| SCHEMBL17918052 | 0.94 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP17A1RAB9A | |
| SCHEMBL24252593 | 0.94 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP17A1RAB9A | |
| SCHEMBL24252242 | 0.94 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP17A1RAB9A | |
| SCHEMBL30857455 | 0.94 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP17A1RAB9A | |
| SCHEMBL17808055 | 0.93 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 | |
| SCHEMBL21725414 | 0.93 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 | |
| SCHEMBL17808030 | 0.93 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP17A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248966-B1 | PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO LTD (JP) | 2022-12-21 | — | — | EP | disclosed |
| CN-107406415-B | Pyrimidine derivative and organic electroluminescent device | 保土谷化学工业株式会社 | 2021-02-19 | — | — | CN | disclosed |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | TYMS, TYMP, DPYD | CYP11B1 2481/4885CYP11B2 2674/4885CYP19A1 1706/4885 |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | TYMS, TYMP, DPYD | CYP11B1 2481/4885CYP11B2 2674/4885CYP19A1 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.