SCHEMBL17918052

SCHEMBL17918052

c1cncc(-c2ccc(-c3cc(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)nc(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)n3)cc2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 7/20 0.68
DHODH Q02127 1/20 0.50
CYP11B2 P19099 6/20 0.48
CYP19A1 P11511 2/20 0.48
CYP17A1 P05093 1/20 0.48
CYP2A6 P11509 2/20 0.44
GPR84 Q9NQS5 1/20 0.44
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
GLA P06280 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
NTSR1 P30989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24252242 1.00 CYP11B1 (0.68) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL30857455 1.00 CYP11B1 (0.68) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL24252593 1.00 CYP11B1 (0.68) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL19650642 0.99 CYP11B1 (0.67) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL30296752 0.99 CYP11B1 (0.67) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL17807971 0.99 CYP11B1 (0.67) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL17918051 0.99 CYP11B1 (0.67) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL19762057 0.97 CYP11B1 (0.65) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL22227765 0.96 CYP11B1 (0.67) CYP11B1DHODHCYP11B2CYP19A1CYP17A1
SCHEMBL17808077 0.95 CYP11B1 (0.62) CYP11B1DHODHCYP11B2CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346015-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-30 US disclosed
US-20170346015-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-30 US disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885DHODH 2619/4885CYP11B2 470/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 CYP11B1 272/4885DHODH 2619/4885CYP11B2 470/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT CYP11B1 450/4885DHODH 1866/4885CYP11B2 394/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885DHODH 8/4885CYP11B2 2329/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885DHODH 8/4885CYP11B2 2329/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B1 1637/4885DHODH 255/4885CYP11B2 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.