⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212144 | 0.97 | — | — | |
| Acetic Acid SCHEMBL8798567 | 0.91 | ALDH1A1 (0.56) | — | |
| SCHEMBL7028823 | 0.91 | CYP1A2 (0.59) | — | |
| SCHEMBL1615423 | 0.88 | CYP1A2 (0.61) | — | |
| SCHEMBL19638401 | 0.86 | CYP1A2 (0.59) | — | |
| SCHEMBL85568 | 0.85 | — | — | |
| SCHEMBL8116488 | 0.85 | CYP1A2 (0.64) | — | |
| SCHEMBL19638363 | 0.84 | CYP1A2 (0.57) | — | |
| SCHEMBL282083 | 0.83 | CYP1A2 (0.61) | — | |
| SCHEMBL24597734 | 0.81 | CYP1A2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936468-B | Compounds with anticancer activity | 协和麒麟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-114502534-A | BET degradant | 协和麒麟株式会社 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021065980-A1 | BET DEGRADER | 協和キリン株式会社 | 2021-04-08 | — | — | WO | disclosed |
| CN-111936468-A | Compounds with anti-cancer activity | 协和麒麟株式会社 | 2020-11-13 | — | — | CN | disclosed |
| US-10577460-B2 | Method for producing polyester | NIPPON SODA CO., LTD. (JP) | 2020-03-03 | — | — | US | disclosed |
| CN-110114343-A | Pyrazolopyrimidine compound and its application method | 豪夫迈·罗氏有限公司 | 2019-08-09 | — | — | CN | disclosed |
| US-20180022867-A1 | METHOD FOR PRODUCING POLYESTER | NIPPON SODA CO., LTD. (JP) | 2018-01-25 | — | — | US | disclosed |
| EP-3248998-A1 | METHOD FOR PRODUCING POLYESTER | Nippon Soda Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |