⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009059 | 1.00 | — | — | |
| SCHEMBL14195896 | 1.00 | — | — | |
| SCHEMBL400389 | 1.00 | — | — | |
| Ethyne SCHEMBL27623976 | 0.95 | SPHK1 (0.35) | — | |
| SCHEMBL402617 | 0.89 | SPHK1 (0.33) | — | |
| Biphenyl SCHEMBL402802 | 0.82 | TAAR1 (0.51) | — | |
| SCHEMBL271971 | 0.81 | — | — | |
| SCHEMBL2512216 | 0.81 | — | — | |
| SCHEMBL13244562 | 0.81 | — | — | |
| SCHEMBL2512211 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591520-B1 | Microorganism producing L-threonine having inactivated tyR gene, method of producing the same and method of producing L-threonine using the microorganism | CJ CHEILJEDANG CORP (KR) | 2017-11-29 | — | — | EP | claimed |
| CN-100379851-C | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2008-04-09 | — | — | CN | claimed |
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | claimed |
| CN-1654634-A | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2005-08-17 | — | — | CN | claimed |
| CN-1654624-A | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2005-08-17 | — | — | CN | claimed |
| CN-118922434-A | Variant L-threonine export proteins and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-11-08 | — | — | CN | disclosed |
| CN-118829649-A | Variant L-threonine export proteins and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-10-22 | — | — | CN | disclosed |
| CN-114630903-B | Modified polypeptides of meso-diaminopimelate dehydrogenase and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-02-06 | — | — | CN | disclosed |
| CN-114729338-B | Variant dihydropyridine dicarboxylic acid reductase polypeptides and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-01-26 | — | — | CN | disclosed |
| CN-114729338-A | Mutant dihydrodipicolinate reductase polypeptide and method for producing L-threonine using the same | CJ第一制糖株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114630903-A | Modified polypeptide of meso-diaminopimelate dehydrogenase and method for producing L-threonine using same | CJ第一制糖株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-106715687-B | Pyruvate dehydrogenase mutant, microorganism comprising mutant, and method for producing L-amino acid by using microorganism | CJ第一制糖株式会社 | 2021-04-27 | — | — | CN | disclosed |
| CN-101072865-A | A microorganism producing l-threonine having an inactivated lysr gene, method for producing the same and method for producing l-threonine using the microorganism | CJ CORP (KR) | 2007-11-14 | — | — | CN | disclosed |
| CN-1296473-C | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2007-01-24 | — | — | CN | disclosed |
| CN-1777577-A | Antibacterial agent | CHIRON CORP (US) | 2006-05-24 | — | — | CN | disclosed |
| CN-1654624-A | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2005-08-17 | — | — | CN | disclosed |
| CN-1654634-A | Microorganism producing l-threonine, method of producing the same and method of producing l-threonine using the microorganism | CJ CORP (KR) | 2005-08-17 | — | — | CN | disclosed |
| CN-1044911-C | Process for preparing prodrug | IGEN INC (US) | 1999-09-01 | — | — | CN | disclosed |
| CN-1217335-A | Method for preparing precursor medicine | IGEN INC (US) | 1999-05-26 | — | — | CN | disclosed |
| CN-1070409-A | Prodrugs activated by targetted catalytic proteins | IGEN INC (US) | 1993-03-31 | — | — | CN | disclosed |