SCHEMBL400389

SCHEMBL400389

C[C@@H](O)[C@H](N)C(=O)NO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19638604 1.00
SCHEMBL25009059 1.00
SCHEMBL14195896 1.00
Ethyne SCHEMBL27623976 0.95 SPHK1 (0.35)
SCHEMBL402617 0.89 SPHK1 (0.33)
Biphenyl SCHEMBL402802 0.82 TAAR1 (0.51)
SCHEMBL271971 0.81
SCHEMBL2512216 0.81
SCHEMBL13244562 0.81
SCHEMBL2512211 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591520-B1 Microorganism producing L-threonine having inactivated tyR gene, method of producing the same and method of producing L-threonine using the microorganism CJ CHEILJEDANG CORP (KR) 2017-11-29 EP claimed
JP-62195293-A None JP disclosed
JP-54089085-A None JP disclosed
US-12584152-B2 L-Threonine export protein variant and method for production of L-Threonine using same CJ CHEILJEDANG CORPORATION (KR) 2026-03-24 US disclosed
US-12553056-B2 Modified polypeptide of meso-diaminopimelate dehydrogenase and polynucleotide encoding the modified polypeptide CJ CHEILJEDANG CORPORATION (KR) 2026-02-17 US disclosed
US-12497626-B2 Variant dihydrodipicolinate reductase polypeptide and method of producing L-threonine using the same CJ CHEILJEDANG CORPORATION (KR) 2025-12-16 US disclosed
US-20250197900-A1 MUTANT L-THREONINE-RELEASING PROTEIN AND METHOD FOR PRODUCING L-THREONINE USING SAME CJ CHEILJEDANG CORPORATION (KR) 2025-06-19 US disclosed
US-20250179127-A1 VARIANT L-THREONINE EXPORT PROTEIN AND METHOD OF PRODUCING L-THREONINE USING SAME CJ CHEILJEDANG CORPORATION (KR) 2025-06-05 US disclosed
EP-4505875-A1 METHOD FOR CONTROLLING PARASITIC PLANTS AJINOMOTO CO., INC. (JP) 2025-02-12 EP disclosed
US-20250031699-A1 Method for Controlling Parasitic Plants AJINOMOTO CO., INC. (JP) 2025-01-30 US disclosed
EP-0746336-A4 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN INC (US) 1996-07-26 EP disclosed
WO-1993002703-A1 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN, INC. (US) 1993-02-18 WO disclosed
JP-S62195293-A PRODUCTION OF L-ISOLEUCINE BY FERMENTATION METHOD KYOWA HAKKO KOGYO CO LTD 1987-08-28 JP disclosed
US-4529697-A Aerobic culture of Brevibacterium or Corynebacterium AJINOMOTO CO., INC. (JP) 1985-07-16 US disclosed
US-4427773-A FROM BREVIBACTERIUM OR CORYNEBACTERIUM TRANSFORMANTS AJINOMOTO COMPANY INCORPORATED (JP) 1984-01-24 US disclosed
US-4389483-A AEROBIC CULTURING A MUTANT OF BREVIBACTERIUM OR COPYNEBACTERIUM AJINOMOTO COMPANY INCORPORATED (JP) 1983-06-21 US disclosed
US-4368266-A MUTANTS OF BREVIBACTERIUM OR CORYNEBACTERIUM REQUIRING ACETIC ACID FOR GROWTH AJINOMOTO COMPANY INCORPORATED (JP) 1983-01-11 US disclosed
US-4347317-A BREVIBACTERIUM OR CORYNEBACTERIUM MUTANTS AJINOMOTO COMPANY, INCORPORATED (JP) 1982-08-31 US disclosed
JP-S5489085-A PREPARATION OF L-GLUTAMIC ACID AJINOMOTO CO INC 1979-07-14 JP disclosed
JP-S05489085-A 0001-01-01 JP disclosed