Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19639411 | 0.99 | KMT2A (0.47) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| Hydrochloric Acid SCHEMBL19639408 | 0.99 | KMT2A (0.47) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| SCHEMBL19639340 | 0.89 | KMT2A (0.50) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| SCHEMBL19639238 | 0.89 | KMT2A (0.50) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| Hydrochloric Acid SCHEMBL19639261 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| Hydrochloric Acid SCHEMBL19639265 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| Hydrochloric Acid SCHEMBL19639283 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| Hydrochloric Acid SCHEMBL19639279 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| SCHEMBL19639250 | 0.88 | KDM4E (0.51) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 | |
| SCHEMBL19639249 | 0.88 | KDM4E (0.51) | KMT2AALDH1A1NPSR1ALOX12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | KMT2A 4411/4885ALDH1A1 1734/4885NPSR1 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.