Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639473 | 0.93 | IKBKB (0.55) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639446 | 0.93 | RARA (0.52) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639495 | 0.91 | RARA (0.52) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639376 | 0.90 | RARA (0.56) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639444 | 0.90 | IKBKB (0.57) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639454 | 0.89 | RARB (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639394 | 0.88 | RARA (0.54) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639485 | 0.88 | RARA (0.49) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19660550 | 0.87 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL19639404 | 0.86 | IKBKB (0.51) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647688-B2 | Compounds, synthesis method thereof and use of same in medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-05-12 | — | — | US | claimed |
| US-20170342040-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-11-30 | — | — | US | claimed |
| EP-3233806-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RES & DEV (FR) | 2021-10-27 | — | — | EP | disclosed |
| US-10647688-B2 | Compounds, synthesis method thereof and use of same in medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-05-12 | — | — | US | disclosed |
| US-10647688-B2 | Compounds, synthesis method thereof and use of same in medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-05-12 | — | — | US | disclosed |
| US-20170342040-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-11-30 | — | — | US | disclosed |
| US-20170342040-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-11-30 | — | — | US | disclosed |
| US-20170342040-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342040-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-10647688-B2 | Compounds, synthesis method thereof and use of same in medicine and in cosmetics | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.