SCHEMBL19640239

SCHEMBL19640239

CCO[Si](C)(C)CCSCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
POLB P06746 1/20 0.44
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44
BLM P54132 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP2D6 P10635 2/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 4/20 0.39
BHMT Q93088 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
TSHR P16473 2/20 0.34
MVD P53602 1/20 0.34
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3334466 0.89 GMNN (0.50) MAPTGMNNTP53POLBTHRB
SCHEMBL16872457 0.83 MAPT (0.46) MAPTGMNNTP53POLBTHRB
SCHEMBL18056843 0.81 GMNN (0.42) MAPTGMNNTP53POLBTHRB
SCHEMBL28348942 0.76 MAPT (0.52) MAPTGMNNTP53POLBTHRB
SCHEMBL851975 0.76 CYP2D6 (0.50) MAPTGMNNTP53POLBTHRB
SCHEMBL27845735 0.74 CYP2D6 (0.48) MAPTGMNNTP53POLBTHRB
SCHEMBL16592783 0.74 FFAR3 (0.40) HSD17B10ALDH1A1TSHR
SCHEMBL28065159 0.73 CYP2C19 (0.38) POLBBLMHSD17B10ALDH1A1
SCHEMBL13301073 0.73 ALDH1A1 (0.37) POLBCYP2C9HSD17B10ALDH1A1SMN1; SMN2
SCHEMBL20994637 0.73 GMNN (0.56) MAPTGMNNTP53POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10246581-B2 Rubber compositions containing whey protein BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2019-04-02 US disclosed
US-20170342253-A1 RUBBER COMPOSITIONS CONTAINING WHEY PROTEIN BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-11-30 US disclosed