SCHEMBL19640281

SCHEMBL19640281

CC(=O)SCC[Si](C)(C)OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.35
BLM P54132 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27523582 0.85 CYP2C19 (0.36) CYP2C19POLBBLMATM
SCHEMBL28346356 0.82 CYP2C19 (0.38) CYP2C19POLBBLMATM
SCHEMBL333630 0.80 TSHR (0.31) CYP2C19
SCHEMBL19640282 0.78 TSHR (0.31)
SCHEMBL29211224 0.78 CYP2C19 (0.34) CYP2C19POLBBLMATM
SCHEMBL28673870 0.78 CYP2C19 (0.40) CYP2C19POLBBLMATM
SCHEMBL28065159 0.74 CYP2C19 (0.38) CYP2C19POLBBLMATM
SCHEMBL333725 0.72 TSHR (0.31) CYP2C19
SCHEMBL12345651 0.72 CYP2C19 (0.46) CYP2C19POLBBLMATM
SCHEMBL705523 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
CN-100422192-C Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2008-10-01 CN claimed
CN-1784412-A Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2006-06-07 CN claimed
CN-1247687-C Mineral filled elastomeric compositions CROMPTON CORP (US) 2006-03-29 CN claimed
CN-1481419-A Mineral filled elastomeric compositions ��³�նٹ�˾ 2004-03-10 CN claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN disclosed
CN-105452261-B continuous process for preparing thiocarboxylate silane 莫门蒂夫性能材料股份有限公司 2019-12-10 CN disclosed
US-10246581-B2 Rubber compositions containing whey protein BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2019-04-02 US disclosed
US-20170342253-A1 RUBBER COMPOSITIONS CONTAINING WHEY PROTEIN BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-11-30 US disclosed
CN-105452261-A Continuous process for the preparation of thiocarboxylate silane MOMENTIVE PERFORMANCE MAT INC 2016-03-30 CN disclosed
CN-101880415-B Silica-rubber mixtures having improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2013-05-22 CN disclosed
CN-1681876-B Silica-rubber mixtures with improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2012-05-30 CN disclosed
CN-100422192-C Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2008-10-01 CN disclosed
CN-1784412-A Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2006-06-07 CN disclosed
CN-1247687-C Mineral filled elastomeric compositions CROMPTON CORP (US) 2006-03-29 CN disclosed
CN-1681876-A Silica-rubber mixtures with improved hardness GEN ELECTRIC (US) 2005-10-12 CN disclosed
CN-1481419-A Mineral filled elastomeric compositions ��³�նٹ�˾ 2004-03-10 CN disclosed