Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | FNTA | P49354 | 5/20 | 0.38 |
| ▸ | FNTB | P49356 | 5/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 2/20 | 0.37 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL9234547 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2FNTA | |
| Arginine SCHEMBL13684847 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2FNTA | |
| Arginine SCHEMBL1766047 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2FNTA | |
| Arginine SCHEMBL15194117 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2FNTA | |
| Arginine SCHEMBL1965664 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2DDAH1 | |
| Arginine SCHEMBL1766048 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2FNTA | |
| Arginine SCHEMBL27842844 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2DDAH1 | |
| Arginine SCHEMBL3898452 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2DDAH1 | |
| Arginine SCHEMBL20996120 | 0.91 | OTC (0.46) | OTCNOS3NOS1NOS2DDAH1 | |
| Threonine SCHEMBL1964086 | 0.91 | FNTA (0.35) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068310-A2 | COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF GENETICALLY MODIFIED PLANT-DERIVED BIOMASS | QTEROS, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011072264-A2 | METHODS AND COMPOSITIONS FOR BIOMASS TREATMENT | QTEROS, INC. (US) | 2011-06-16 | — | — | WO | disclosed |