⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22793020 | 0.79 | — | — | |
| SCHEMBL24109472 | 0.76 | GANAB (0.32) | — | |
| SCHEMBL15533333 | 0.74 | — | — | |
| SCHEMBL21969217 | 0.74 | — | — | |
| SCHEMBL24663757 | 0.72 | — | — | |
| SCHEMBL21360187 | 0.72 | — | — | |
| SCHEMBL10050841 | 0.71 | — | — | |
| SCHEMBL22928100 | 0.71 | — | — | |
| SCHEMBL13926397 | 0.70 | — | — | |
| SCHEMBL15760928 | 0.69 | CCR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091481-B2 | Heterocyclic compounds, preparation and methods and uses thereof | InventisBio Co., Ltd. (CN) | 2021-08-17 | — | — | US | disclosed |
| US-20210198255-A1 | HETEROCYCLIC COMPOUNDS, PREPARATION AND METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-07-01 | — | — | US | disclosed |
| US-10988466-B2 | Heterocyclic derivatives useful as SHP2 inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-20200392128-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |
| US-20170342230-A1 | CHEMICAL BLOWING AGENT AND THERMALLY EXPANDABLE THERMOPLASTIC COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2017-11-30 | — | — | US | disclosed |
| CN-106605174-A | Pattern forming method, composition for forming protective film, method for manufacturing electronic component, and electronic component | 富士胶片株式会社 | 2017-04-26 | — | — | CN | disclosed |
| CN-104254520-B | The method being isomerized to 3 allyl acetonitriles along 2 allyl acetonitriles | 巴斯夫欧洲公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-104254520-A | Process for isomerizing cis-2-pentenenitrile to 3-pentenenitriles | BASF SE | 2014-12-31 | — | — | CN | disclosed |