Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766 | 0.97 | ALOX5 (0.70) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL29349675 | 0.97 | ALOX5 (0.70) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| Charcoal, Activated SCHEMBL31491466 | 0.94 | ALOX5 (0.67) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL31438327 | 0.94 | ALOX5 (0.67) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL30218500 | 0.94 | ALOX5 (0.67) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL6170559 | 0.94 | ALOX5 (0.67) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| Hydrazine SCHEMBL26615185 | 0.88 | ALOX5 (0.61) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL3066757 | 0.82 | ALOX5 (0.54) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL29450289 | 0.80 | ALOX5 (1.00) | ALOX5POLBKDM4EALDH1A1PARP1 | |
| SCHEMBL291774 | 0.80 | ALOX5 (1.00) | ALOX5POLBKDM4EALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017202496-A1 | USE OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE IN THE TREATMENT OF INFLAMMATORY AND/OR DEGENERATIVE DISORDERS OF THE LIGAMENTS OF THE JOINTS, ARTICULAR CAPSULES AND BURSAE | METRIOPHARM AG (CH) | 2017-11-30 | — | — | WO | claimed |
| WO-2023179905-A1 | COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AND A FUMARIC ACID ESTER | METRIOPHARM AG (CH) | 2023-09-28 | — | — | WO | disclosed |
| CN-105859634-B | 5- amino -2,3- dihydro-(2,3- benzodiazine) -1,4- dione sodium salt crystal form | 梅特里奥药品股份公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-105859634-A | Crystalline form of 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt | 梅特里奥药品股份公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105726541-A | Crystalline Forms For 5-Amino-2,3-Dihydrophthalazine-1,4-Dione Sodium Salt, Pharmaceutical Preparations Containing The Same And Method For The Production Of Said Forms | 梅特里奥药品股份公司 | 2016-07-06 | — | — | CN | disclosed |