Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.46 |
| ▸ | WNT1 | P04628 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12059966 | 0.87 | CHRNA7 (0.70) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1965159 | 0.87 | CHRNA7 (0.70) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL12315101 | 0.84 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1963062 | 0.84 | CHRNA7 (0.63) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| Formic Acid SCHEMBL1966715 | 0.83 | CHRNA7 (0.65) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1966473 | 0.82 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL15199691 | 0.81 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1965825 | 0.81 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1964878 | 0.80 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL5996566 | 0.80 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130217683-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USE THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217683-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USE THEREOF | CHRNA7, CHRNA5, CHRNA3 | CHRNA7 1/4885HTR3A 352/4885DYRK1A 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.