SCHEMBL19643109

SCHEMBL19643109

Cc1ccccc1C(=O)Oc1cccc2c1oc1c(OC(=O)c3ccccc3C)cccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.65
ESR1 P03372 3/20 0.65
ESR2 Q92731 3/20 0.65
MEN1 O00255 3/20 0.65
PKM P14618 1/20 0.51
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 3/20 0.43
LMNA P02545 3/20 0.43
CYP2C9 P11712 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19643108 0.87 ESR1 (0.51) KMT2AESR1ESR2MEN1PKM
SCHEMBL19642796 0.85 ESR1 (0.65) KMT2AESR1ESR2MEN1POLB
SCHEMBL8431592 0.82 KMT2A (0.68) KMT2AESR1ESR2MEN1PKM
SCHEMBL27948132 0.81 KMT2A (0.73) KMT2AESR1ESR2MEN1PKM
SCHEMBL28731362 0.80 KMT2A (0.67) KMT2AESR1ESR2MEN1PKM
SCHEMBL10457215 0.80 KMT2A (0.66) KMT2AESR1ESR2MEN1PKM
SCHEMBL19656171 0.78 KMT2A (0.61) KMT2AESR1ESR2MEN1POLB
SCHEMBL28684978 0.77 KMT2A (0.70) KMT2AESR1ESR2MEN1PKM
SCHEMBL20646377 0.76 KMT2A (0.61) KMT2AESR1ESR2MEN1PKM
SCHEMBL10626086 0.76 KMT2A (0.70) KMT2AESR1ESR2MEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464391-B1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS BRASKEM AMERICA INC (US) 2024-01-03 EP claimed
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US claimed
CN-109790238-B Non-phthalate donors for polyolefin catalysts 布拉斯科美国公司 2021-12-31 CN claimed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US claimed
US-10662267-B2 Non-phthalate donor for polyolefin catalysts W.R. GRACE & CO. -CONN. (US) 2020-05-26 US claimed
US-20190270831-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W. R. GRACE & CO. - CONN. 2019-09-05 US claimed
EP-3464391-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. Grace & Co.-Conn. (US) 2019-04-10 EP claimed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO claimed
EP-3464391-B1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS BRASKEM AMERICA INC (US) 2024-01-03 EP disclosed
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
US-11291981-B2 Boron-based electron donors for Ziegler-Natta catalyst systems BRASKEM AMERICA, INC. (US) 2022-04-05 US disclosed
CN-109790238-B Non-phthalate donors for polyolefin catalysts 布拉斯科美国公司 2021-12-31 CN disclosed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US disclosed
US-20190270831-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W. R. GRACE & CO. - CONN. 2019-09-05 US disclosed
EP-3464391-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. Grace & Co.-Conn. (US) 2019-04-10 EP disclosed
WO-2019036376-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS BRASKEM AMERICA, INC. (US) 2019-02-21 WO disclosed
US-20190046965-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS BRASKEM AMERICA, INC. 2019-02-14 US disclosed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO disclosed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO disclosed