Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880798 | 1.00 | HIF1A (0.36) | HIF1AALDH1A1POLRMT | |
| SCHEMBL17453462 | 1.00 | HIF1A (0.36) | HIF1AALDH1A1POLRMT | |
| SCHEMBL21880466 | 0.87 | HIF1A (0.36) | HIF1APOLRMT | |
| SCHEMBL17453472 | 0.87 | HIF1A (0.36) | HIF1APOLRMT | |
| SCHEMBL17453473 | 0.87 | HIF1A (0.36) | HIF1APOLRMT | |
| SCHEMBL17465448 | 0.86 | — | — | |
| SCHEMBL17465453 | 0.86 | — | — | |
| SCHEMBL21137110 | 0.84 | HIF1A (0.33) | HIF1AALDH1A1 | |
| SCHEMBL21880481 | 0.83 | HIF1A (0.35) | HIF1AALDH1A1 | |
| SCHEMBL19644632 | 0.83 | HIF1A (0.35) | HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828388-B2 | Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-11-28 | — | — | US | disclosed |