Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453469 | 1.00 | HIF1A (0.35) | HIF1AALDH1A1 | |
| SCHEMBL17453477 | 0.90 | HIF1A (0.35) | HIF1AALDH1A1 | |
| SCHEMBL21880481 | 0.90 | HIF1A (0.35) | HIF1AALDH1A1 | |
| SCHEMBL17465445 | 0.86 | — | — | |
| SCHEMBL21137373 | 0.86 | HIF1A (0.34) | HIF1AALDH1A1 | |
| SCHEMBL21880798 | 0.83 | HIF1A (0.36) | HIF1AALDH1A1 | |
| SCHEMBL19644605 | 0.83 | HIF1A (0.36) | HIF1AALDH1A1 | |
| SCHEMBL17453462 | 0.83 | HIF1A (0.36) | HIF1AALDH1A1 | |
| SCHEMBL19644648 | 0.83 | HIF1A (0.35) | HIF1A | |
| SCHEMBL19644599 | 0.82 | HIF1A (0.35) | HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174870-B1 | THIENO [3,2-D]PYRIMIDINES, FURO [3,2,D]PYRIMIDINES AND PYRROLO [3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2020-04-15 | — | — | EP | disclosed |
| US-9828388-B2 | Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-11-28 | — | — | US | disclosed |