Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644661 | 0.88 | HIF1A (0.32) | HIF1A | |
| SCHEMBL24591624 | 0.83 | HIF1A (0.31) | HIF1A | |
| SCHEMBL19644590 | 0.77 | HIF1A (0.32) | HIF1A | |
| SCHEMBL21880480 | 0.77 | — | — | |
| SCHEMBL24591606 | 0.77 | — | — | |
| SCHEMBL19644580 | 0.77 | HIF1A (0.30) | HIF1A | |
| SCHEMBL21137374 | 0.76 | HIF1A (0.33) | HIF1A | |
| SCHEMBL17453461 | 0.75 | HIF1A (0.35) | HIF1A | |
| SCHEMBL21137368 | 0.73 | HIF1A (0.33) | HIF1A | |
| SCHEMBL21880508 | 0.73 | HIF1A (0.31) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828388-B2 | Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-11-28 | — | — | US | disclosed |