⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880480 | 1.00 | — | — | |
| SCHEMBL19962233 | 0.89 | HIF1A (0.32) | — | |
| SCHEMBL19644659 | 0.77 | HIF1A (0.32) | — | |
| SCHEMBL19644661 | 0.77 | HIF1A (0.32) | — | |
| SCHEMBL24591619 | 0.76 | — | — | |
| SCHEMBL19962846 | 0.74 | HIF1A (0.32) | — | |
| SCHEMBL24591618 | 0.73 | HIF1A (0.30) | — | |
| SCHEMBL21137368 | 0.73 | HIF1A (0.33) | — | |
| SCHEMBL21137374 | 0.73 | HIF1A (0.33) | — | |
| SCHEMBL24591624 | 0.72 | HIF1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023650-A1 | 4'-SUBSTITUTED-FURO[3,2-D]PYRIMIDINE AND -PYRROLO[3,2- D]PYRIMIDINE DERIVATIVES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |