Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 6/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | HINT1 | P49773 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18061565 | 1.00 | TGM2 (0.51) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12849789 | 0.88 | TGM2 (0.58) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12878145 | 0.88 | TGM2 (0.58) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12799375 | 0.88 | TGM2 (0.58) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL18061560 | 0.88 | TGM2 (0.58) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12849790 | 0.88 | NT5E (0.56) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12799371 | 0.88 | NT5E (0.56) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL19822430 | 0.88 | NT5E (0.56) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL12878136 | 0.88 | NT5E (0.56) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL18061808 | 0.88 | NT5E (0.56) | TGM2NT5ETAS1R3TAS1R1FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828410-B2 | β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment | Atea Pharmaceuticals, Inc. (US) | 2017-11-28 | — | — | US | disclosed |