Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067110 | 1.00 | NT5E (0.40) | NT5ECA12CA1CA2CA9 | |
| SCHEMBL18061705 | 0.92 | CA12 (0.39) | NT5ECA12CA1CA2CA9 | |
| SCHEMBL21136209 | 0.90 | CA12 (0.35) | NT5ECA12CA1CA2CA9 | |
| SCHEMBL18067162 | 0.89 | ADORA1 (0.41) | NT5ECA12CA1CA2CA9 | |
| SCHEMBL21015197 | 0.85 | HTR2C (0.32) | P2RY1HTR2CHTR2B | |
| SCHEMBL19644818 | 0.83 | CA5A (0.47) | NT5EP2RY1CA5AP2RY11 | |
| SCHEMBL20841357 | 0.83 | HTR2C (0.31) | HTR2CHTR2B | |
| SCHEMBL19822431 | 0.83 | NT5E (0.43) | NT5EP2RY12BLMP2RY1CA5A | |
| SCHEMBL18061636 | 0.82 | P2RY1 (0.45) | NT5ECA12CA1CA2CA9 | |
| SCHEMBL18061566 | 0.81 | P2RY1 (0.47) | NT5EENPP1P2RY12P2RY1P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828410-B2 | β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment | Atea Pharmaceuticals, Inc. (US) | 2017-11-28 | — | — | US | disclosed |