Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 13/20 | 0.72 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.72 |
| ▸ | CLK2 | P49760 | 6/20 | 0.55 |
| ▸ | CLK3 | P49761 | 5/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645032 | 0.92 | WNT1 (0.60) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL15868940 | 0.90 | WNT1 (0.80) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL19645023 | 0.89 | WNT1 (0.66) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL15862825 | 0.89 | WNT1 (0.81) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL15370922 | 0.89 | WNT1 (0.76) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587245 | 0.88 | WNT1 (0.63) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL15370920 | 0.88 | WNT1 (0.77) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17638430 | 0.87 | WNT1 (0.65) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587244 | 0.87 | WNT1 (0.64) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17638429 | 0.86 | WNT1 (0.65) | WNT1TGFBR1CLK2CLK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828372-B2 | 2-(1H-indazol-3-yl)-1H-imidazo[4,5-C]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828372-B2 | 2-(1H-indazol-3-yl)-1H-imidazo[4,5-C]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-11-28 | — | — | US | disclosed |