Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855109 | 0.93 | GAA (0.40) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19861159 | 0.91 | MEN1 (0.49) | MEN1MAPTKMT2AATML3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27574672 | 0.91 | MEN1 (0.49) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19645194 | 0.85 | GAA (0.43) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL28617178 | 0.85 | GAA (0.43) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL20198651 | 0.85 | MAPT (0.46) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL20076474 | 0.85 | DGKA (0.50) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL20457453 | 0.82 | FFAR1 (0.48) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19861329 | 0.82 | FFAR1 (0.48) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL5973054 | 0.81 | GAA (0.50) | CYP4F2CYP4A11GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |