Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434918 | 0.85 | SCN9A (0.32) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL2221215 | 0.85 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL2223995 | 0.85 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL1444883 | 0.85 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL2221226 | 0.85 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL17801583 | 0.85 | SCN9A (0.32) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL288363 | 0.85 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL22467822 | 0.85 | SCN9A (0.32) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL20973259 | 0.85 | SCN9A (0.32) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL17801581 | 0.85 | SCN9A (0.32) | L3MBTL3L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334677-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010022076-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-02-25 | — | — | WO | disclosed |